One of those places that words can't really do justice to.
No matter what you're looking for, you can probably find it on the Strip. The drinks and gambling are a given, of course, but the people watching is spectacular (as Derek mentioned). You can find things there you won't find anywhere else.
Such an interesting spot that it's hard to believe that a collection like this could be in Cincinnati. Any kind of sign you can think of from every era, and the guided tour gives you an excellent history lesson. Perfect way to spend an afternoon.
When the weather's nice, the place to be is Washington Park. Always stuff going on, and right by tons of restaurants and Music Hall.
Cool spot. Nature trails were closed when I went up, but that view of downtown is hard to beat.
I'm a big fan of this place. Tons of beers on draft, and their food is pretty good, and decently priced.
If you're a baseball fan, you owe it to yourself to check out one of the history of baseball's oldest team. They have tons of artifacts from every era of Reds baseball, from the 19th century to the Big Red Machine. If you go, see if you can take the ballpark tour as well, you won't regret it.
Come for the trivia night, stay for the pool tables. There are a bunch of them. Really divey place, but the bartenders are friendly and drinks are cheap.
Went here last weekend to check out the hiking trails and wasn't disappointed. Not too difficult, but good views and a nice place to be on a nice day.